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FOR WHAT REASON

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Julia

Julia Report 24 May 2010 12:05

If you take statins, why are you not supposed to eat grapefruit.
Julia in Derbyshire

Researching:
Turner Cambs/.Northants, Singapore and Penang,Trengrove Singapore and Penang, Arnull (Champion Race Horse Breeders & Trainers 'Oleander')Germany and Denmark

Elisabeth

Elisabeth Report 24 May 2010 12:15

Just found this on a Google search:

The Interaction Between Grapefruit and Statins
Grapefruit contains the compound bergamottin, which interacts with certain enzyme systems in the body, such as cytochrome P-450 and P-glycoprotein. These enzyme systems are responsible for breaking down statins, as well as other drugs, into more usable chemicals and transporting them in the body.
When grapefruit juice is consumed at or around the time you take your statin, the components in grapefruit prevent these enzyme systems from breaking down the drug, causing the drug to accumulate in high amounts in the body. This can be very dangerous and can cause a variety of health problems, such as liver damage or a rare condition called rhabdomyolysis (severe muscle and kidney damage).


Doesn't look good, does it?

Elisabeth

MrDaff

MrDaff Report 24 May 2010 12:34

Quite a lot of drugs, apart from statins, are affected by grapefruit and grapefruit juices... it wasn't allowed on the haemotology ward I was on, at all.... I was told that the rule of thumb is or should be... whatever the drug, check first whether grapefruit will affect your metabolism, and so encourage the build up of chemical toxins... ok for short term use, but not if you are taking something long term.

Love

Daff xxxxx